2-Mercaptobenzothiazole home ICD10: L23.9

2-Mercaptobenzothiazole

Formula CAS
C7H5NS2 149-30-4



Background
Mercaptobenzothiazole is a thiazole rubber accelerator which are the most common accelerators used in the production of rubber. Accelerators are agents used to speed up the vulcanization process of cross-linking polymer chains. Mercaptobenzothiazole is the most commonly identified allergen in allergic contact dermatitis due to shoes in the United States and accounts for 15% to 45% of positive patch tests in patients tested in various series for shoe dermatitis. Mercaptobenzothiazole is second to the thiurams as the etiologic agent in allergic contact dermatitis due to gloves.

Synonyms
2-Benzathiazalethiol
2-Mercaptobenzothiazole
Captax
Dermacid
MBT
Mercaptobenzothiazole
Mertax
Nocceler M
Rotax
Thiotax

Uses
Accelerator
Anticorrosive agents
Antifreeze
Cements and adhesives
Condoms and diaphragms
Cutting oils
Detergents
Flea and tick powder
Fungicides
Gloves (household, work, or hospital)
Greases
Leather shoes (insoles, adhesive linings)
Medical devices
Photographic film emulsion
Renal dialysis equipment
Retarder
Rubber in undergarments and clothing
Rubber pillows and sheets
Rubber shoes (sneakers, tennis shoes, etc.)
Sponge makeup applicators and rubber eyelash curlers
Swimwear
Tires and tubes
Toys
Veterinarian products such as tick and flea powders and sprays

Cross-Reactions

Unusual Reactions

Back to list of contact allergens


Referenties
1. Ancona A, Suárez de la Torre R, Evia JR. Dermatitis from mercaptobenzothiazole in a Foley catheter. Contact Dermatitis 1985;13(5):339-340.
2. Foussereau J, Muslmani M, Cavelier C, Herve-Bazin B. Contact allergy to safety shoes. Contact Dermatitis 1986 ;14(4):233-236.
3. Wilkinson SM, Cartwright PH, English JS. Allergic contact dermatitis from mercaptobenzothiazole in a releasing fluid. Contact Dermatitis 1990;23(5):370.
4. Saha M, Srinivas CR, Shenoy SD, Balachandran C, Acharya S. Footwear dermatitis. Contact Dermatitis 1993;28(5):260-264.


Auteur(s):
dr. Jan R. Mekkes. Dermatoloog, Amsterdam UMC.

12-08-2023 (JRM) - www.huidziekten.nl W3C-html-4.01-valid