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Formula |
CAS |
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C9H11NO2 |
94-09-7 |
CAS: Chemical Abstract Service Registry Number
Background
Benzocaine is a p-aminobenzoic acid used as a local anesthetic. Benzocaine-sensitive individuals do not react with lidocaine.
Synonyms
4-Aminobenzoic acid ethyl ester
Aethoform
Americaine
Anesthone
Anesthesin
Benzocaine
Ethyl aminobenzoate
Ethyl-p-aminobenzoate
Orthesin
p-Aminobenzoic acid ethyl ester
Parathesin
Uses
Appetite suppressants
Astringents and analgesics
Burn and sunburn remedies
Cough tablets, drops, and lozenges
Hemorrhoidal creams, suppositories, and enemas
Oral and gingival products for teething, toothaches, canker sores,
and denture irritation and in oral antibacterial agents
Podiatric products for athlete's foot, corns, calluses, and warts
Poison ivy products
Sore throat sprays and lozenges
Cross-Reactions
Butethamine
Hydrochlorothiazide
PABA and esters
Procainamide
Hydrochlorothiazide
Azo/aniline dyes
Paraphenylenediamine
Sulfonylureas
4-aminosalicylic acid
Parabens
Para compounds
Unusual Reactions
Photoallergy
Contact urticaria
References
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1. |
Maibach, H.I. and H.L. Johnson, Contact urticaria syndrome. Contact urticaria to diethyltoluamide (immediate-type hypersensitivity). Archives of Dermatology, 1975. 111(6): p. 726-30. |
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2. |
Marzulli, F.N. and H.I. Maibach, Contact allergy: predictive testing in man. Contact Dermatitis, 1976. 2(1): p. 1-17. |
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3. |
Fisher, A.A., Dermatitis due to benzocaine present in sunscreens containing glyceryl PABA (Escalol 106). Contact Dermatitis, 1977. 3(3): p. 170-1. |
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4. |
Fisher, A.A., Fifty years experience with contact dermatitis. Cutis, 1977. 19(1): p. 18-20, 26-32. |
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5. |
Husain, S.L., Contact dermatitis in the West of Scotland. Contact Dermatitis, 1977. 3(6): p. 327-32. |
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6. |
Caro, I., Contact allergy/photo allergy to glyceryl PABA and benzocaine. Contact Dermatitis, 1978. 4(6): p. 381-2. |
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7. |
Angelini, G. and C.L. Meneghini, Oral tests in contact allergy to para-amino compounds. Contact Dermatitis, 1981. 7(6): p. 311-4. |
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8. |
Angelini, G., G.A. Vena, and C.L. Meneghini, Allergic contact dermatitis to some medicaments. Contact Dermatitis, 1985. 12(5): p. 263-9. |
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9. |
Kreilgard, B., J. Hansen, and T. Fischer, Chemical, pharmaceutical and clinical standardization of the TRUE Test caine mix. Contact Dermatitis, 1989. 21(1): p. 23-7. |
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10. |
Fisher, A.A., A "current contact news" follow-up: controversial subjects and those resulting in litigation [news]. Cutis, 1993. 52(5): p. 254-6. |
13-06-2011
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