Betamethasone-17-valerate (Betnelan)

codes geen / geen

 

 

Formula

CAS

C27H37FO6

2152-44-5

 
CAS: Chemical Abstract Service Registry Number
 

Background

Betamethasone-17-valerate is a high-potency topical fluorinated corticosteroid with low systemic effects. It has been classified as group D by Coopman et al. According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups. 

 

Synonyms

Betamethasone-17-valerate

Betnelan
Bedermin
Betnesol-V
Betneval
Betnovate
Bextasol
Celestan-V
Celestoderm-V
Dermosol
Dermovaleas
Ecoval 70
Hormezon
Tokuderm
Valisone

 

Uses

Topical and systemic corticosteroid

 

Cross-Reactions

Goup D Corticosteroids
Alclomethasone dipropionate
Betamethasone dipropionate
Betamethasone valerate
Clobetasone-17-butyrate
Clobetasone-17-propionate
Fluocortolone caproate
Fluocortolone pivalate
Fluprenidene acetate
Hydrocortisone-17-butyrate
Hydrocortisone-17-valerate

 

Unusual Reactions

 

 

References

1.

Pasricha, J.S. and R. Gupta, Contact sensitivity to betamethasone 17-valerate and fluocinolone acetonide. Contact Dermatitis, 1983. 9(4): p. 330-1.

2.

Koch, E.M., Contact allergic reaction to valerate esters of betamethasone and hydrocortisone. Contact Dermatitis, 1985. 12(1): p. 58.

3.

Nakajima, H., S. Mohri, and R. Nagai, A case of contact dermatitis due to betamethasone valerate--with a review of Japanese articles. Journal of Dermatology, 1986. 13(6): p. 467-70.

4.

Coopman, S., H. Degreef, and A. Dooms-Goossens, Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. British Journal of Dermatology, 1989. 121(1): p. 27-34.

5.

Dunkel, F.G., P. Elsner, and G. Burg, Contact allergies to topical corticosteroids: 10 cases of contact dermatitis. [Review]. Contact Dermatitis, 1991. 25(2): p. 97-103.

6.

Hisa, T., et al., Contact allergies to topical corticosteroids. Contact Dermatitis, 1993. 28(3): p. 174-9.

7.

Lepoittevin, J.P., J. Drieghe, and A. Dooms-Goossens, Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids [see comments]. Archives of Dermatology, 1995. 131(1): p. 31-7.

 

 

 

 

 

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