Formula |
CAS |
C27H37FO6 |
2152-44-5 |
CAS: Chemical Abstract Service Registry Number
Background
Betamethasone-17-valerate is a high-potency topical fluorinated corticosteroid
with low systemic effects. It has been classified as group D by Coopman
et al. According the A-D grouping, patch-test reactions occur 6-7 times
more frequently within well-defined groups of structurally related chemicals
than between corticosteroids of different groups.
Synonyms
Betamethasone-17-valerate
Betnelan
Bedermin
Betnesol-V
Betneval
Betnovate
Bextasol
Celestan-V
Celestoderm-V
Dermosol
Dermovaleas
Ecoval 70
Hormezon
Tokuderm
Valisone
Uses
Topical and systemic corticosteroid
Cross-Reactions
Goup D Corticosteroids
Alclomethasone dipropionate
Betamethasone dipropionate
Betamethasone valerate
Clobetasone-17-butyrate
Clobetasone-17-propionate
Fluocortolone caproate
Fluocortolone pivalate
Fluprenidene acetate
Hydrocortisone-17-butyrate
Hydrocortisone-17-valerate
Unusual Reactions
References
1.
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Pasricha,
J.S. and R. Gupta, Contact sensitivity to betamethasone
17-valerate and fluocinolone acetonide. Contact Dermatitis, 1983. 9(4):
p. 330-1.
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2.
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Koch,
E.M., Contact allergic reaction to valerate esters of betamethasone
and hydrocortisone. Contact Dermatitis, 1985. 12(1): p. 58.
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3.
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Nakajima,
H., S. Mohri, and R. Nagai, A case of contact dermatitis
due to betamethasone valerate--with a review of Japanese articles.
Journal of Dermatology, 1986. 13(6): p. 467-70.
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4.
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Coopman, S., H.
Degreef, and A. Dooms-Goossens, Identification
of cross-reaction patterns in allergic contact dermatitis from topical
corticosteroids. British Journal of Dermatology, 1989. 121(1):
p. 27-34.
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5.
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Dunkel,
F.G., P. Elsner, and G. Burg, Contact allergies to topical corticosteroids: 10 cases of contact dermatitis. [Review]. Contact
Dermatitis, 1991. 25(2): p. 97-103.
|
6.
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Hisa,
T., et al., Contact allergies to topical corticosteroids.
Contact Dermatitis, 1993. 28(3): p. 174-9.
|
7.
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Lepoittevin,
J.P., J. Drieghe, and A. Dooms-Goossens, Studies
in patients with corticosteroid contact allergy. Understanding cross-reactivity
among different steroids [see comments]. Archives of Dermatology, 1995. 131(1): p. 31-7.
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19-06-2011
(JRM) - www.huidziekten.nl
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