Formula |
CAS |
C4H7Cl3O |
57-15-8 |
CAS: Chemical Abstract Service Registry Number
Background
Chlorobutanol is used as a preservative and antiseptic. It is also a plasticizer
for cellulose esters and ethers.
Synonyms
Chlorobutanol
1,1,1-Trichloro-2-methyl-2-propanol
b,b,b-Trichloro-tert-butyl alcohol
Acetone chloroform
Chlorbutol
Chloretone
Coliquifilm
Methaform
Sedaform
Uses
Otic (ear) preparations
Opthalmic (eye) preparations
Dental analgesics
Sedatives
Antiseptics
Cellulose esters and ethers
Hypodermic solutions
Cross-Reactions
Unusual Reactions
References
1.
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Fisher,
A.A., F. Pascher, and N.B. Kanof, Allergic contact dermatitis
due to ingredients of vehicles. A "vehicle tray" for patch testing.
Archives of Dermatology, 1971. 104(3): p. 286-90.
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2.
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Kroon, S.,
Contact dermatitis from oleyl polypeptide in Xeruminex
ear drops. Contact Dermatitis, 1981. 7(5): p. 271-2.
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3.
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Hofmann,
H., G. Goerz, and G. Plewig, Anaphylactic shock from
chlorobutanol-preserved oxytocin. Contact Dermatitis, 1986. 15(4):
p. 241.
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4.
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Valsecchi, R. and T.
Cainelli, Contact allergy to Cerumenex.
Contact Dermatitis, 1988. 18(5): p. 312.
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5.
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Balato,
N., et al., Allergic contact dermatitis from Cerumenex
in a child. Contact Dermatitis, 1989. 21(5): p. 348-9.
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21-07-2011
(JRM) - www.huidziekten.nl
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