Cobalt chloride

codes geen / geen

 

 

 

Formula

CAS

Cl2Co

7791-13-1

 
CAS: Chemical Abstract Service Registry Number
 

Background

Cobalt is a gray, hard, magnetic, ductile, somewhat malleable metal. It is used in the manufacture of alloys and cobalt salts. It is an essential trace mineral and is present in vitamin B12.
Various salts of cobalt are colored and are used as pigments in colored glass and pottery as well as in makeup and hair dyes.
Approximately 80% of individuals sensitive to cobalt are also found to be sensitive to either or both chromate and nickel.
Probably the most common source of exposure to cobalt is nickel-plated objects, which practically always contain cobalt.
Patch testing with cobalt chloride may yield an unusual false-positive response consisting of tiny purpuric papules.

 

Synonyms

Cobalt
Cobalt (II) chloride-hexahydrate
Cobalt blue
Cobalt chloride
Cobaltous chloride

 

Uses

Antiperspirants
Cement, paint, resins
Electroplating
Fertilizer and feed additive
Foam stabilizer in beer
Hand etching and grinding
Hair dyes and cosmetics
Invisible ink
Jewelry
Joint replacements and dental appliances
Machinery parts
Pigments in pottery, glass, and crayons
Polyester resin manufacture
Shell splinters
Snaps, zippers, buttons, buckles
Tools, utensils, instruments
Vitamin B12

 

Cross-Reactions

 

 

Unusual Reactions

Airborne contact dermatitis
Erythema multiforme-like eruption
Non-immunologic contact urticaria
Photocontact dermatitis

 

References

1.

Gaul, L.E., Incidence of sensitivity to chromium, nickel, gold, silver, and copper compared to reactions to their aqueous salts including cobalt sulphate. Annals of Allergy, 1954. 12: p. 429.

2.

Gimenez Camarasa, J.M., Cobalt contact dermatitis. Acta Dermato-Venereologica, 1967. 47(5): p. 287-92.

3.

Smith, J.D., R.B. Odom, and H.I. Maibach, Contact urticaria from cobalt chloride. Archives of Dermatology, 1975. 111(12): p. 1610-1.

4.

Spruit, D. and K.E. Malten, Occupational cobalt and chromium dermatitis in an offset printing factory. Dermatologica, 1975. 151(1): p. 34-42.

5.

Anonymous, Standardization of patch tests in Japan. Contact Dermatitis, 1976. 2(4): p. 205-11.

6.

Cohen, H.A., The role of carrier in sensitivity to chromium and cobalt. Archives of Dermatology, 1976. 112(1): p. 37-9.

7.

Veien, N.K. and K. Kaaber, Latent metal hypersensitivity among patients with pompholyx. Contact Dermatitis, 1976. 2(6): p. 361.

8.

Husain, S.L., Contact dermatitis in the West of Scotland. Contact Dermatitis, 1977. 3(6): p. 327-32

9.

Krook, G., S. Fregert, and B. Gruvberger, Chromate and cobalt eczema due to magentic tapes. Contact Dermatitis, 1977. 3(1): p. 60-1.

10.

Wahlberg, J.E., Routine patch testing with cadmium chloride. Contact Dermatitis, 1977. 3(6): p. 293-6.

11.

Fregert, S. and B. Gruvberger, Solubility of cobalt in cement. Contact Dermatitis, 1978. 4(1): p. 14-8.

12.

Sertoli, A., et al., Unusual contact dermatitis to a cobalt salt. Contact Dermatitis, 1978. 4(5): p. 314.

13.

Veien, N.K. and E. Svejgaard, Lymphocyte transformation in patients with cobalt dermatitis. British Journal of Dermatology, 1978. 99(2): p. 191-6.

14.

14. Wahlberg, J.E. and A. Boman, Sensitization and testing of guinea pigs with cobalt chloride. Contact Dermatitis, 1978. 4(3): p. 128-32.

15.

Camarasa, J.M., First epidemiological study of contact dermatitis in Spain - 1977. Spanish Contact Dermatitis Research Group. Acta Dermato-Venereologica. Supplementum, 1979. 59(85): p. 33-7.

16.

Einarsson, O., et al., Dissolution of cobalt from hard metal alloys by cutting fluids. Contact Dermatitis, 1979. 5(3): p. 129-32.

17.

Kaaber, S., H. Thulin, and E. Nielsen, Skin sensitivity to denture base materials in the burning mouth syndrome. Contact Dermatitis, 1979. 5(2): p. 90-6.

18.

Meneghini, C. and G. Angelini, Intradermal test in contact allergy to metals. Acta Dermato-Venereologica. Supplementum, 1979. 59(85): p. 123-4.

19.

Menne, T. and E. Bachmann, Permanent disability from hand dermatitis in females sensitive to nickel, chromium and cobalt. Dermatosen in Beruf und Umwelt. Occupational & Environmental Dermatoses, 1979. 27(5): p. 129-35.

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Roed-Petersen, B., J. Roed-Petersen, and K.D. Jorgensen, Nickel allergy and osteomyelitis in a patient with metal osteosynthesis of a jaw fracture. Contact Dermatitis, 1979. 5(2): p. 108-12.

21.

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22.

Sugai, T., et al., Age distribution of the incidence of contact sensitivity to standard allergens. Contact Dermatitis, 1979. 5(6): p. 383-8.

23.

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24.

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25.

Menne, T., Relationship between cobalt and nickel sensitization in females. Contact Dermatitis, 1980. 6(5): p. 337-40.

26.

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28.

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29.

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30.

Price, M.L. and D.M. MacDonald, Cheilitis and cobalt allergy related to ingestion of vitamin B12. Contact Dermatitis, 1981. 7(6): p. 352.

31.

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32.

Cook, L.J., Associated nickel and cobalt contact dermatitis presenting as erythema multiforme. Contact Dermatitis, 1982. 8(4): p. 280-1.

33.

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34.

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35.

Fischer, T. and I. Rystedt, Cobalt allergy in hard metal workers. Contact Dermatitis, 1983. 9(2): p. 115-21.

36.

Fischer, T., et al., HLA-A, -B, -C and -DR antigens and positive patch test reactions. Contact Dermatitis, 1983. 9(6): p. 524-5.

37.

Hubler, W.R., Jr. and W.R. Hubler, Sr., Dermatitis from a chromium dental plate. Contact Dermatitis, 1983. 9(5): p. 377-83.

38.

Rystedt, I. and T. Fischer, Relationship between nickel and cobalt sensitization in hard metal workers. Contact Dermatitis, 1983. 9(3): p. 195-200.

39.

Veien, N.K., et al., Oral challenge with metal salts. (I). Vesicular patch-test-negative hand eczema. Contact Dermatitis, 1983. 9(5): p. 402-6.

40.

Veien, N.K., et al., Oral challenge with metal salts. (II). Various types of eczema. Contact Dermatitis, 1983. 9(5): p. 407-10.

41.

Fischer, T., et al., HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt. Acta Dermato-Venereologica, 1984. 64(2): p. 121-4.

42.

42. Fisher, A.A., Purpuric contact dermatitis. Cutis, 1984. 33(4): p. 346, 349, 351.

43.

Fregert, S. and B. Gruvberger, Blue and black pottery as a potential source of cobalt. Contact Dermatitis, 1984. 10(1): p. 50.

44.

Kalimo, K. and K. Lammintausta, 24 and 48 h allergen exposure in patch testing. Comparative study with 11 common contact allergens and NiCl2. Contact Dermatitis, 1984. 10(1): p. 25-9.

45.

Lantinga, H., J.P. Nater, and P.J. Coenraads, Prevalence, incidence and course of eczema on the hands and forearms in a sample of the general population. Contact Dermatitis, 1984. 10(3): p. 135-9.

46.

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47.

van Ketel, W.G., Simultaneous sensitization to gum arabic and cobalt. Contact Dermatitis, 1984. 10(3): p. 180.

48.

Alomar, A., L. Conde-Salazar, and C. Romaguera, Occupational dermatoses from cutting oils. Contact Dermatitis, 1985. 12(3): p. 129-38.

49.

Fischer, T. and H. Maibach, Aluminium in Finn chambers reacts with cobalt and nickel salts in patch test materials. Contact Dermatitis, 1985. 12(4): p. 200-2.

50.

Fischer, T. and I. Rystedt, False-positive, follicular and irritant patch test reactions to metal salts. Contact Dermatitis, 1985. 12(2): p. 93-8.

51.

Garcia, J. and A. Armisen, Cement dermatitis with isolated cobalt sensitivity. Contact Dermatitis, 1985. 12(1): p. 52.

52.

Lammintausta, K., et al., Interrelationship of nickel and cobalt contact sensitization. Contact Dermatitis, 1985. 13(3): p. 148-52.

53.

Larsson-Stymne, B. and L. Widstrom, Ear piercing--a cause of nickel allergy in schoolgirls?. Contact Dermatitis, 1985. 13(5): p. 289-93.

54.

Menne, T., Flare-up of cobalt dermatitis from Antabuse treatment. Contact Dermatitis, 1985. 12(1): p. 53.

55.

55. Nilsson, E., Contact sensitivity and urticaria in "wet" work. Contact Dermatitis, 1985. 13(5): p. 321-8.

56.

Waterman, A.H. and J.J. Schrik, Allergy in hip arthroplasty. Contact Dermatitis, 1985. 13(5): p. 294-301.

57.

Dooms-Goossens, A.E., et al., Contact dermatitis caused by airborne agents. A review and case reports. Journal of the American Academy of Dermatology, 1986. 15(1): p. 1-10.

58.

Gawkrodger, D.J., et al., Contact clinic survey of nickel-sensitive subjects. Contact Dermatitis, 1986. 14(3): p. 165-9.

59.

Goh, C.L., S.L. Gan, and S.J. Ngui, Occupational dermatitis in a prefabrication construction factory. Contact Dermatitis, 1986. 15(4): p. 235-40.

60.

Goh, C.L., S.F. Kwok, and S.L. Gan, Cobalt and nickel content of Asian cements. Contact Dermatitis, 1986. 15(3): p. 169-72.

61.

Moller, H. and A. Svensson, Metal sensitivity: positive history but negative test indicates atopy. Contact Dermatitis, 1986. 14(1): p. 57-60.

62.

Singgih, S.I., et al., Occupational hand dermatoses in hospital cleaning personnel. Contact Dermatitis, 1986. 14(1): p. 14-9.

63.

Lammintausta, K. and K. Kalimo, Do positive nickel reactions increase nonspecific patch test reactivity?. Contact Dermatitis, 1987. 16(3): p. 160-3.

64.

Vilaplana, J., et al., Cobalt content of household cleaning products. Contact Dermatitis, 1987. 16(3): p. 139-41.

65.

Foussereau, J. and C. Cavelier, Short communications. Allergic contact dermatitis from cobalt in the rubber industry. Contact Dermatitis, 1988. 19(3): p. 217.

66.

Gilboa, R., N.G. Al-Tawil, and J.A. Marcusson, Metal allergy in cashiers. An in vitro and in vivo study for the presence of metal allergy. Acta Dermato-Venereologica, 1988. 68(4): p. 317-24.

67.

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68.

68. Matsunaga, K., et al., Occupational allergic contact dermatitis in beauticians. Contact Dermatitis, 1988. 18(2): p. 94-6.

69.

Vilaplana, J., et al., Cobalt content of household cleaning products [letter]. Contact Dermatitis, 1988. 18(4): p. 254-5.

70.

Allenby, C.F. and D.A. Basketter, Minimum eliciting patch test concentrations of cobalt. Contact Dermatitis, 1989. 20(3): p. 185-90.

71.

Avnstorp, C., Follow-up of workers from the prefabricated concrete industry after the addition of ferrous sulphate to Danish cement. Contact Dermatitis, 1989. 20(5): p. 365-71.

72.

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73.

Cavelier, C., et al., Allergy to nickel or cobalt: tolerance to nickel and cobalt samples in man and in the guinea pig allergic or sensitized to these metals. Contact Dermatitis, 1989. 21(2): p. 72-8.

74.

Macfarlane, A.W., et al., Delayed patch test reactions at days 7 and 9. Contact Dermatitis, 1989. 20(2): p. 127-32.

75.

Moller, H., Intradermal testing in doubtful cases of contact allergy to metals. Contact Dermatitis, 1989. 20(2): p. 120-3.

76.

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77.

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78.

Kiec-Swierczynska, M., Allergy to chromate, cobalt and nickel in Lodz 1977-1988. Contact Dermatitis, 1990. 22(4): p. 229-31.

79.

Kiec-Swierczynska, M., Occupational dermatoses and allergy to metals in Polish construction workers manufacturing prefabricated building units. Contact Dermatitis, 1990. 23(1): p. 27-32.

80.

Meding, B., Epidemiology of hand eczema in an industrial city. Acta Dermato-Venereologica. Supplementum, 1990. 153: p. 1-43.

81.

Meding, B. and G. Swanbeck, Occupational hand eczema in an industrial city. Contact Dermatitis, 1990. 22(1): p. 13-23.

82.

Szliska, C. and J. Raskoski, Sensitization to nickel, cobalt and chromium in surgical patients. Contact Dermatitis, 1990. 23(5): p. 378-9.

83.

83. de la Cuadra, J. and M. Grau-Massanes, Occupational contact dermatitis from rhodium and cobalt. Contact Dermatitis, 1991. 25(3): p. 182-4.

84.

Edman, B., Computerized analysis of concomitant contact allergens. Contact Dermatitis, 1991. 24(2): p. 110-3.

85.

Eedy, D.J., D. Burrows, and D. McMaster, The nickel content of certain commercially available metallic patch test materials and its relevance in nickel-sensitive subjects. Contact Dermatitis, 1991. 24(1): p. 11-5.

86.

Massone, L., et al., Positive patch test reactions to nickel, cobalt, and potassium dichromate in a series of 576 patients. Cutis, 1991. 47(2): p. 119-22.

87.

Shehade, S.A., M.H. Beck, and V.F. Hillier, Epidemiological survey of standard series patch test results and observations on day 2 and day 4 readings. Contact Dermatitis, 1991. 24(2): p. 119-22.

88.

Vilaplana, J., C. Romaguera, and F. Grimalt, Contact dermatitis from nickel and cobalt in a contact lens cleaning solution. Contact Dermatitis, 1991. 24(3): p. 232-3.

89.

Zhang, X.M., B. Niklasson, and S.Y. Li, Patch testing in cases of eczema and dermatitis in Beijing, China. Contact Dermatitis, 1991. 25(4): p. 224-9.

90.

Castiglioni, G., et al., Results of routine patch testing of 834 patients in Turin. Contact Dermatitis, 1992. 27(3): p. 182-5.

91.

de Fine Olivarius, F. and T. Menne, Skin reactivity to metallic cobalt in patients with a positive patch test to cobalt chloride. Contact Dermatitis, 1992. 27(4): p. 241-3.

92.

Goncalo, S., et al., Allergic contact dermatitis in children. A multicenter study of the Portuguese Contact Dermatitis Group (GPEDC). Contact Dermatitis, 1992. 26(2): p. 112-5.

93.

Basketter, D.A., et al., Nickel, cobalt and chromium in consumer products: a role in allergic contact dermatitis?. [Review]. Contact Dermatitis, 1993. 28(1): p. 15-25.

94.

Gawkrodger, D.J. and F.M. Lewis, Isolated cobalt sensitivity in an etcher. Contact Dermatitis, 1993. 29(1): p. 46.

95.

Tandon, R. and B. Aarts, Chromium, nickel and cobalt contents of some Australian cements. Contact Dermatitis, 1993. 28(4): p. 201-5.

96.

Tarvainen, K., et al., Exposure, skin protection and occupational skin diseases in the glass-fibre-reinforced plastics industry. Contact Dermatitis, 1993. 29(3): p. 119-27.

97.

97. Dotterud, L.K. and E.S. Falk, Metal allergy in north Norwegian schoolchildren and its relationship with ear piercing and atopy. Contact Dermatitis, 1994. 31(5): p. 308-13.

98.

Fitzgerald, D.A. and J.S. English, Lymphoedema of the hands as a complication of chronic allergic contact dermatitis. Contact Dermatitis, 1994. 30(5): p. 310.

99.

Kokelj, F., et al., Nickel, chromate and cobalt in toilet soaps analysed by inductively coupled plasma mass spectrometry. Contact Dermatitis, 1994. 31(4): p. 270.

100.

Sevila, A., et al., Contact dermatitis in children. Contact Dermatitis, 1994. 30(5): p. 292-4.

101.

Veien, N.K., et al., Stomatitis or systemically-induced contact dermatitis from metal wire in orthodontic materials. Contact Dermatitis, 1994. 30(4): p. 210-3.

102.

Vilaplana, J., C. Romaguera, and F. Cornellana, Contact dermatitis and adverse oral mucous membrane reactions related to the use of dental prostheses. Contact Dermatitis, 1994. 30(2): p. 80-4.

103.

Zenorola, P., M. Bisceglia, and M. Lomuto, Ashy dermatosis associated with cobalt allergy. Contact Dermatitis, 1994. 31(1): p. 53-4.

104.

Fischer, T., et al., Skin disease and contact sensitivity in house painters using water-based paints, glues and putties. Contact Dermatitis, 1995. 32(1): p. 39-45.

105.

Meijer, C., et al., Ear piercing, and nickel and cobalt sensitization, in 520 young Swedish men doing compulsory military service. Contact Dermatitis, 1995. 32(3): p. 147-9.

 

 

 

 

 

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