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Formula |
CAS |
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97-23-4 |
CAS: Chemical Abstract Service Registry Number
Background
Dichlorophene is a fungicide and bactericide used in dentifrices, shampoos,
antiperspirant and deodorant creams, powder, toilet waters, and preparations
for dermatophytosis of the foot. It is also used extensively as a mildewcide
to treat and preserve cotton fibers, various fabrics, paper, synthetic
leather lattices, and some adhesive tape backings.
Dichlorophene is a more potent sensitizer than hexachlorophene. Although
closely related chemically, they rarely cross-react. The U.S. Food and
Drug Administration has restricted greatly the use of hexachlorophene for
its possible toxic, but not allergic, effect.
Synonyms
2,2-Dihydroxydiphenylmethane
Antiphen
Cuniphen
Dicestal
Dichlorophen
Dichlorophene
Didroxane
G-4 (Compound G4)
Hyosan
Parabis
Teniathane
Teniatol
Westpuril
Uses
Bandages (soft casts)
Cosmetics
Dentifrices, toothpaste, and mouthwashes
Deodorants
Foot powders
Shampoos
Soaps and cleansers
Treated fabrics, papers, adhesives, and bandages.
Cross-Reactions
Hexachlorophene
Unusual Reactions
References
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1. |
Fisher, A.A. and I. Tobin, Sensitivity to compound G-4 ('Dichlorophene') in dentrifices. Journal of The American Medical Association, 1953. 151: p. 988. |
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2. |
Epstein, E., Dichlorophene allergy. Annals of Allergy, 1966. 24: p. 437. |
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3. |
Schorr, W.F., Dichlorphene (G-4) allergy. Archives of Dermatology, 1970. 102: p. 515. |
13-08-2011
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