Formula |
CAS |
C6H6O2 |
123-31-9 |
CAS: Chemical Abstract Service Registry Number
Background
Hydroquinone is a reducing agent, photographic developer, antioxidant and
depigmenting agent. It is an inhibitor of acrylic monomers.
Synonyms
1,4-Benzendil
1,4-Dihydroxybenzol
Aida
Black and White Bleaching Cream
Eldoquin
Elopaque
quinnone
Tecquinol
Dihydroxybenzene
Hydroquinone
Hydroquinol
p-Dihydroxybenzene
p-Diphenol
p-Hydroxyphenol
Quinol
Uses
Acrylyic manufacturing
Antioxidant makers
Bacteriostatic agent makers
Dental prosthesis
Drug Makers
Eldoquin
Eldoplaque
Fur processors
Melanex (Neutrogena)
Motor fuel blenders
Organic chemical synthesizers
Paint makers
Photography: developers
Plastic stabilizer workers
Rubber antioxidant
Solaquin
Stone coating workers
Styrene monomer workers
Cross-Reactions
Resorcinol
Unusual Reactions
Depigmentation
Productkenmerken (Summary in
Dutch)
Hydrochinon
is een depigmenterend middel, het is ook een anti-oxydans met reducerende
werking. Het wordt ook gebruikt bij het ontwikkelen van films. Hydrochinon is bij inname
toxisch. Als huidblekend middel gebruikt kan hydrochinon bij langdurig gebruik
(> 6 maanden) de melanocyt vernietigen, waardoor pigmentloze plekken ontstaan,
aanvankelijk op de opbrengplaatsen, later ook op niet-behandelde delen
van de huid. Hydrochinon is darnaast één van de oorzaken
van exogene ochronose. Kenmerkend zijn de zwarte vlekken op de huid (waardoor
patiënten daar juist méér hydrochinon gaan smeren). In dierproeven is hydrochinin kankerverwekkend en blijkt geboorteafwijkingen
te kunnen veroorzaken en nefrotoxisch te zijn.
Producten
waar het in voorkomt:
x
Allergeen testsubstantie: x
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References
1.
|
Kaaber, S., H.
Thulin, and E. Nielsen, Skin sensitivity to denture
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2.
|
Frenk, E. and P.
Loi-Zedda, Occupational depigmentation due to
a hydroquinone-containing photographic developer. Contact Dermatitis,
1980. 6(3): p. 238-9.
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3.
|
Kersey,
P. and C.J. Stevenson, Vitiligo and occupational exposure to hydroquinone
from servicing self-photographing machines. Contact Dermatitis, 1981. 7(5):
p. 285-7.
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4.
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Whittington,
C.V., Hypopigmentation from UV resin additive.
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|
5.
|
Fisher,
A.A., Leukoderma from bleaching creams containing 2%
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|
6.
|
van der
Walle, H.B., L.P. Delbressine, and E. Seutter, Concomitant
sensitization to hydroquinone and P-methyoxyphenol in the guinea pig; inhibitors
in acrylic monomers. Contact Dermatitis, 1982. 8(3): p. 147-54.
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7.
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8.
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van
Ketel, W.G., Sensitization to hydroquinone and the monobenzyl
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|
9.
|
Boyle, J. and
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11.
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12.
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Liden, C.,
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13.
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14.
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15.
|
Torres, V., et al.,
Allergic contact cheilitis and stomatitis
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16.
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Camarasa,
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17.
|
Fisher,
A.A., Differential diagnosis of idiopathic vitiligo
from contact leukoderma. Part II: Leukoderma due to cosmetics and bleaching
creams [news]. Cutis, 1994. 53(5): p. 232-4.
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10-12-2011
(JRM) - www.huidziekten.nl
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