Hydroquinone

codes geen / geen

 

 

Formula

CAS

C6H6O2

123-31-9

 
CAS: Chemical Abstract Service Registry Number
 

Background

Hydroquinone is a reducing agent, photographic developer, antioxidant and depigmenting agent. It is an inhibitor of acrylic monomers.

 

Synonyms

1,4-Benzendil
1,4-Dihydroxybenzol
Aida
Black and White Bleaching Cream
Eldoquin
Elopaque
quinnone
Tecquinol
Dihydroxybenzene
Hydroquinone
Hydroquinol
p-Dihydroxybenzene
p-Diphenol
p-Hydroxyphenol
Quinol

 

Uses

Acrylyic manufacturing
Antioxidant makers
Bacteriostatic agent makers
Dental prosthesis
Drug Makers
Eldoquin
Eldoplaque
Fur processors
Melanex (Neutrogena)
Motor fuel blenders
Organic chemical synthesizers
Paint makers
Photography: developers
Plastic stabilizer workers
Rubber antioxidant
Solaquin
Stone coating workers
Styrene monomer workers

 

Cross-Reactions

Resorcinol

 

Unusual Reactions

Depigmentation

 

   

Productkenmerken (Summary in Dutch)

Hydrochinon is een depigmenterend middel, het is ook een anti-oxydans met reducerende werking. Het wordt ook gebruikt bij het ontwikkelen van films. Hydrochinon is bij inname toxisch. Als huidblekend middel gebruikt kan hydrochinon bij langdurig gebruik (> 6 maanden) de melanocyt vernietigen, waardoor pigmentloze plekken ontstaan, aanvankelijk op de opbrengplaatsen, later ook op niet-behandelde delen van de huid. Hydrochinon is darnaast één van de oorzaken van exogene ochronose. Kenmerkend zijn de zwarte vlekken op de huid (waardoor patiënten daar juist méér hydrochinon gaan smeren). In dierproeven is hydrochinin kankerverwekkend en blijkt geboorteafwijkingen te kunnen veroorzaken en nefrotoxisch te zijn.

 

Producten waar het in voorkomt: 

x

 

Allergeen testsubstantie: x

 

 

References

 1.

Kaaber, S., H. Thulin, and E. Nielsen, Skin sensitivity to denture base materials in the burning mouth syndrome. Contact Dermatitis, 1979. 5(2): p. 90-6.

 2.

Frenk, E. and P. Loi-Zedda, Occupational depigmentation due to a hydroquinone-containing photographic developer. Contact Dermatitis, 1980. 6(3): p. 238-9.

 3.

Kersey, P. and C.J. Stevenson, Vitiligo and occupational exposure to hydroquinone from servicing self-photographing machines. Contact Dermatitis, 1981. 7(5): p. 285-7.

 4.

Whittington, C.V., Hypopigmentation from UV resin additive. Contact Dermatitis, 1981. 7(6): p. 289-92.

 5.

Fisher, A.A., Leukoderma from bleaching creams containing 2% hydroquinone. Contact Dermatitis, 1982. 8(4): p. 272-3.

 6.

van der Walle, H.B., L.P. Delbressine, and E. Seutter, Concomitant sensitization to hydroquinone and P-methyoxyphenol in the guinea pig; inhibitors in acrylic monomers. Contact Dermatitis, 1982. 8(3): p. 147-54.

 7.

Romaguera, C. and F. Grimalt, Dermatitis from PABA and hydroquinone. Contact Dermatitis, 1983. 9(3): p. 226.

 8.

van Ketel, W.G., Sensitization to hydroquinone and the monobenzyl ether of hydroquinone. Contact Dermatitis, 1984. 10(4): p. 253.

 9.

Boyle, J. and C.T. Kennedy, Leukoderma from hydroquinone [letter]. Contact Dermatitis, 1985. 13(4): p. 287-8.

10.

Romaguera, C. and F. Grimalt, Leukoderma from hydroquinone. Contact Dermatitis, 1985. 12(3): p. 183.

11.

Das, M. and A. Tandon, Occupational vitiligo. Contact Dermatitis, 1988. 18(3): p. 184-5.

12.

Liden, C., Occupational dermatoses at a film laboratory. Follow-up after modernization. Contact Dermatitis, 1989. 20(3): p. 191-200.

13.

Markey, A.C., A.K. Black, and R.J. Rycroft, Confetti-like depigmentation from hydroquinone. Contact Dermatitis, 1989. 20(2): p. 148-9.

14.

Bajaj, A.K., S.C. Gupta, and A.K. Chatterjee, Hearing aid depigmentation. Contact Dermatitis, 1992. 27(2): p. 126-7.

15.

Torres, V., et al., Allergic contact cheilitis and stomatitis from hydroquinone in an acrylic dental prosthesis. Contact Dermatitis, 1993. 29(2): p. 102-3.

16.

Camarasa, J.G. and E. Serra-Baldrich, Exogenous ochronosis with allergic contact dermatitis from hydroquinone. Contact Dermatitis, 1994. 31(1): p. 57-8.

17.

Fisher, A.A., Differential diagnosis of idiopathic vitiligo from contact leukoderma. Part II: Leukoderma due to cosmetics and bleaching creams [news]. Cutis, 1994. 53(5): p. 232-4.

 

 

 

 

 

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