Promethazine hydrochloride

codes geen / geen

 

 

Formula

CAS

C17H21ClN2S

58-33-3

 
CAS: Chemical Abstract Service Registry Number
 

Background

Promethazine hydrochloride is an antihistamine and antiemetic.

 

Synonyms

Atosil
Dimapp
Duplamin
Fargan
Fenazil
Ganphen
Lergigan
Phencen
Phenergan
Promethazine hydrochloride
Provigan
Prorex
Diphergan
Ganphen
Fellozine
Remsed
Dorme
Fenergan
Lergigan
Phencen
Phergan
Promantine
Promethegan
Promine
Protazine
Prothazin
Thiergan
Prorex
Prothazine
Provigan
Remsed
Vallgerine
N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine
10-(2-Dimethylaminopropyl)phenothiazine
10-(2-Dimethylamino-2-methylethyl)phenothiazine
N-(2´-dimethylamino-2´-methyl)ethylphenothiazine
Proazamine
RP 3277
RP 3389
Hiberna
Vallergine

 

Uses

Anti-emetic pill, syrup, injection
Anti-cough syrup
Antihistamine

 

Cross-Reactions

Phenothiazines
Ethylenediamine hydrochloride
Para compounds
Chlorpromazine hydrochloride
Tripelennamine
Azo dyes

 

Unusual Reactions

Erythema multiforme-like reactions
Photoallergy
Contact urticaria
Persistant light reaction

 

References

 1.

Suurmond, D., Patch test reactions to phenergan cream, promethazine and triethanolamine. Dermatologica, 1966. 133: p. 503.

 2.

King, C.M. and M. Beck, Oral promethazine hydrochloride in ethylenediamine-sensitive patients. Contact Dermatitis, 1983. 9(6): p. 444-7.

 3.

Wennersten, G., et al., The Scandinavian multicenter photopatch study. Preliminary results. Contact Dermatitis, 1984. 10(5): p. 305-9.

 4.

Angelini, G., G.A. Vena, and C.L. Meneghini, Allergic contact dermatitis to some medicaments. Contact Dermatitis, 1985. 12(5): p. 263-9.

 5.

Fisher, A.A., Lack of cross-reaction between promethazine and ethylenediamine [letter]. Contact Dermatitis, 1987. 16(4): p. 236.

 6.

Menz, J., S.A. Muller, and S.M. Connolly, Photopatch testing: a six-year experience [see comments]. Journal of the American Academy of Dermatology, 1988. 18(5 Pt 1): p. 1044-7.

 7.

Edman, B., Computerized analysis of concomitant contact allergens. Contact Dermatitis, 1991. 24(2): p. 110-3.

 8.

Holzle, E., et al., Photopatch testing: the 5-year experience of the German, Austrian, and Swiss Photopatch Test Group. Journal of the American Academy of Dermatology, 1991. 25(1 Pt 1): p. 59-68.

 

 

 

 

 

Terug naar overzicht contact-allergenen08-01-2012 (JRM) -  www.huidziekten.nl