Formula |
CAS |
C17H21ClN2S |
58-33-3 |
CAS: Chemical Abstract Service Registry Number
Background
Promethazine hydrochloride is an antihistamine and antiemetic.
Synonyms
Atosil
Dimapp
Duplamin
Fargan
Fenazil
Ganphen
Lergigan
Phencen
Phenergan
Promethazine hydrochloride
Provigan
Prorex
Diphergan
Ganphen
Fellozine
Remsed
Dorme
Fenergan
Lergigan
Phencen
Phergan
Promantine
Promethegan
Promine
Protazine
Prothazin
Thiergan
Prorex
Prothazine
Provigan
Remsed
Vallgerine
N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine
10-(2-Dimethylaminopropyl)phenothiazine
10-(2-Dimethylamino-2-methylethyl)phenothiazine
N-(2´-dimethylamino-2´-methyl)ethylphenothiazine
Proazamine
RP 3277
RP 3389
Hiberna
Vallergine
Uses
Anti-emetic pill, syrup, injection
Anti-cough syrup
Antihistamine
Cross-Reactions
Phenothiazines
Ethylenediamine hydrochloride
Para compounds
Chlorpromazine hydrochloride
Tripelennamine
Azo dyes
Unusual Reactions
Erythema multiforme-like reactions
Photoallergy
Contact urticaria
Persistant light reaction
References
1.
|
Suurmond, D.,
Patch test reactions to phenergan cream, promethazine
and triethanolamine. Dermatologica, 1966. 133: p. 503.
|
2.
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King,
C.M. and M. Beck, Oral promethazine hydrochloride in ethylenediamine-sensitive
patients. Contact Dermatitis, 1983. 9(6): p. 444-7.
|
3.
|
Wennersten, G., et al.,
The Scandinavian multicenter photopatch
study. Preliminary results. Contact Dermatitis, 1984. 10(5):
p. 305-9.
|
4.
|
Angelini, G.,
G.A. Vena, and C.L. Meneghini, Allergic contact
dermatitis to some medicaments. Contact Dermatitis, 1985. 12(5):
p. 263-9.
|
5.
|
Fisher,
A.A., Lack of cross-reaction between promethazine and
ethylenediamine [letter]. Contact Dermatitis, 1987. 16(4): p.
236.
|
6.
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Menz, J.,
S.A. Muller, and S.M. Connolly, Photopatch testing:
a six-year experience [see comments]. Journal of the American Academy
of Dermatology, 1988. 18(5 Pt 1): p. 1044-7.
|
7.
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Edman, B.,
Computerized analysis of concomitant contact allergens.
Contact Dermatitis, 1991. 24(2): p. 110-3.
|
8.
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Holzle, E., et al.,
Photopatch testing: the 5-year experience
of the German, Austrian, and Swiss Photopatch Test Group. Journal of
the American Academy of Dermatology, 1991. 25(1 Pt 1): p. 59-68.
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08-01-2012
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