|
Formula |
CAS |
|
C11H19NOS |
26530-20-1 |
CAS: Chemical Abstract Service Registry Number
Background
2-n-Octyl-4-isothiazolin-3-one is a member of the chemically realted isothiazolinone
group of preservatives. In a recent Danish study (Nielsen), 2-n-Octyl-4-isothiazolin-3-one
was registered as a component in 16 products with 5 being preservatives.
The isothiazolinone preservatives include: 2-n-Octyl-4-isothiazolin-3-one,
1,2-Benzisothiazolin-3-one, 2-methyl-4-isothiazolin-3-one, and 5-Chloro-2-methyl-4-isothiazolin-3-one.
Synonyms
2-n-Octyl-4-isothiazolin-3-one
2-Octyl-4-isothiazolin-3-one
2-Octyl-3(2H)-isothiazolone
Octhilinone
Kathon 893
RH-893
Skane M-8
Uses
Cooling-tower water
Cosmetics
Cutting oils
Leather preservation
Paints
Shampoos
Wallpaper adhesive
Cross-Reactions
Unusual Reactions
References
|
1. |
Thormann, J., Contact dermatitis to a new fungicide, 2-n-octyl-4-isothiazolin-3-one. Contact Dermatitis, 1982. 8(3): p. 204. |
|
2. |
Mathias, C.G., K.E. Andersen, and K. Hamann, Allergic contact dermatitis from 2-n-octyl-4-isothiazolin-3-one, a paint mildewcide. Contact Dermatitis, 1983. 9(6): p. 507-9. |
|
3. |
Andersen, K.E. and N.K. Veien, Biocide patch tests. Contact Dermatitis, 1985. 12(2): p. 99-103. |
|
4. |
Emmett, E.A., et al., The irritancy and allergenicity of 2-n-octyl-4-isothiazolin-3-one (Skane M-8), with recommendations for patch test concentration. Contact Dermatitis, 1989. 20(1): p. 21-6. |
|
5. |
Nielsen, H., Occupational exposure to isothiazolinones. A study based on a product register. Contact Dermatitis, 1994. 31(1): p. 18-21. |
20-08-2011
(JRM) - www.huidziekten.nl