4-Chloro-3-cresol (PCMC)

codes geen / geen

 

 

Formula

CAS

C7H7ClO

59-50-7

 
CAS: Chemical Abstract Service Registry Number
 

Background

4-Chloro-3-cresol is an antiseptic, desinfectans, and fungicide.

 

Synonyms

4-Chloro-3-cresol
4-Chloro-3 -methylphenol
3-Methyl-4-chlorophenol
2-Chloro-5-hydroxytoluene
6-Chloro-m-cresol
6-Chloro-3-hydroxytoluene
Chlorocresol
Ottafect
p-Chloro-M-Cresol
Parachlorometacresol
PCMC
Phenol, 4-chloro-3-methyl
Preventol CMK

 

Uses

Adhesives and glues
Baby cosmetics
Cooling fluids
Cosmetics shampoos and baby cosmetics
Creams
Inks, paints, and varnishes
Metalworking fluids
Packing materials
Pharmaceutical products corticosteroid creams
Tanning agents
Textile finishes
Topical antiseptics and disinfectants

 

Cross-Reactions

4-chloro3-xylenol

 

Unusual Reactions

Immunologic contact urticaria
Non-immunologic contact urticaria

 

References

1.

Oleffe, J.A., A. Blondeel, and A. de Coninck, Allergy to chlorocresol and propylene glycol in a steroid cream. Contact Dermatitis, 1979. 5(1): p. 53-4.

2.

Dooms-Goossens, A., et al., Chlorocresol and chloracetamide: allergens in medications, glues, and cosmetics. Contact Dermatitis, 1981. 7(1): p. 51-2.

3.

Andersen, K.E. and K. Hamann, How sensitizing is chlorocresol? Allergy tests in guinea pigs versus the clinical experience. Contact Dermatitis, 1984. 11(1): p. 11-20.

4.

Archer, C.B. and D.M. MacDonald, Chlorocresol sensitivity induced by treatment of allergic contact dermatitis with steroid creams. Contact Dermatitis, 1984. 11(3): p. 144-5.

5.

Andersen, K.E., et al., Contact sensitivity and bioavailability of chlorocresol. Contact Dermatitis, 1985. 13(4): p. 246-51.

6.

Andersen, K.E. and N.K. Veien, Biocide patch tests. Contact Dermatitis, 1985. 12(2): p. 99-103.

7.

Andersen, K.E., Contact allergy to chlorocresol, formaldehyde and other biocides. Guinea pig tests and clinical studies. Acta Dermato-Venereologica. Supplementum, 1986. 125: p. 1-21.

8.

Freitas, J.P. and F.M. Brandao, Contact urticaria to chlorocresol. Contact Dermatitis, 1986. 15(4): p. 252.

9.

Goncalo, M., S. Goncalo, and A. Moreno, Immediate and delayed sensitivity to chlorocresol. Contact Dermatitis, 1987. 17(1): p. 46-7.

10.

Lewis, P.G. and E.A. Emmett, Irritant dermatitis from tri-butyl tin oxide and contact allergy from chlorocresol. Contact Dermatitis, 1987. 17(3): p. 129-32.

11.

Zemtsov, A., et al., Evaluation of antigenic determinant in chlorocresol and chloroxylenol contact dermatitis by patch testing with chemically related substances. American Journal of Contact Dermatitis, 1994. 5(1): p. 19-21.

 

 

 

 

 

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