4-Chloro-3-cresol (PCMC)

codes geen / geen

 

 

Formula

CAS

C7H7ClO

59-50-7

 
CAS: Chemical Abstract Service Registry Number
 

Background

4-Chloro-3-cresol is an antiseptic, desinfectans, and fungicide.

 

Synonyms

4-Chloro-3-cresol
4-Chloro-3 -methylphenol
3-Methyl-4-chlorophenol
2-Chloro-5-hydroxytoluene
6-Chloro-m-cresol
6-Chloro-3-hydroxytoluene
Chlorocresol
Ottafect
p-Chloro-M-Cresol
Parachlorometacresol
PCMC
Phenol, 4-chloro-3-methyl
Preventol CMK

 

Uses

Adhesives and glues
Baby cosmetics
Cooling fluids
Cosmetics ‹ shampoos and baby cosmetics
Creams
Inks, paints, and varnishes
Metalworking fluids
Packing materials
Pharmaceutical products ‹ corticosteroid creams
Tanning agents
Textile finishes
Topical antiseptics and disinfectants

 

Cross-Reactions

4-chloro3-xylenol

 

Unusual Reactions

Immunologic contact urticaria
Non-immunologic contact urticaria

 

References

1.

Oleffe, J.A., A. Blondeel, and A. de Coninck, Allergy to chlorocresol and propylene glycol in a steroid cream. Contact Dermatitis, 1979. 5(1): p. 53-4.

2.

Dooms-Goossens, A., et al., Chlorocresol and chloracetamide: allergens in medications, glues, and cosmetics. Contact Dermatitis, 1981. 7(1): p. 51-2.

3.

Andersen, K.E. and K. Hamann, How sensitizing is chlorocresol? Allergy tests in guinea pigs versus the clinical experience. Contact Dermatitis, 1984. 11(1): p. 11-20.

4.

Archer, C.B. and D.M. MacDonald, Chlorocresol sensitivity induced by treatment of allergic contact dermatitis with steroid creams. Contact Dermatitis, 1984. 11(3): p. 144-5.

5.

Andersen, K.E., et al., Contact sensitivity and bioavailability of chlorocresol. Contact Dermatitis, 1985. 13(4): p. 246-51.

6.

Andersen, K.E. and N.K. Veien, Biocide patch tests. Contact Dermatitis, 1985. 12(2): p. 99-103.

7.

Andersen, K.E., Contact allergy to chlorocresol, formaldehyde and other biocides. Guinea pig tests and clinical studies. Acta Dermato-Venereologica. Supplementum, 1986. 125: p. 1-21.

8.

Freitas, J.P. and F.M. Brandao, Contact urticaria to chlorocresol. Contact Dermatitis, 1986. 15(4): p. 252.

9.

Goncalo, M., S. Goncalo, and A. Moreno, Immediate and delayed sensitivity to chlorocresol. Contact Dermatitis, 1987. 17(1): p. 46-7.

10.

Lewis, P.G. and E.A. Emmett, Irritant dermatitis from tri-butyl tin oxide and contact allergy from chlorocresol. Contact Dermatitis, 1987. 17(3): p. 129-32.

11.

Zemtsov, A., et al., Evaluation of antigenic determinant in chlorocresol and chloroxylenol contact dermatitis by patch testing with chemically related substances. American Journal of Contact Dermatitis, 1994. 5(1): p. 19-21.

 

 

 

 

 

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