Formula |
CAS |
C20H30O2 |
514-10-3 |
BackgroundAbietic acid (abietinic acid or sylvic acid)
is an organic compound that occurs widely in trees. It is the primary component
of resin acid, is the primary irritant in pine wood and resin, isolated from
rosin (via isomerization) and is the most abundant of several closely related
organic acids that constitute most of rosin, the solid portion of the oleoresin
of coniferous trees. Its ester or salt is called an abietate. Abietic acid is
extracted from tree rosin. It belongs to the abietane diterpene group of organic
compounds derived from four isoprene units. It is used in lacquers, varnishes,
and soaps, and for the analysis of resins and the preparation of metal resinates,
plastics and paper. It is found in Pinus insularis (Khasi Pine), Pinus kesiya
Royle, Pinus strobus (Eastern White Pine), and Pinus sylvestris (Scots Pine).
Rosin has been used for centuries for caulking ships. It is also rubbed on the
bows of musical instruments to make them less slippery. Resin acids are converted
into ester gum by reaction with controlled amounts of glycerol or other polyhydric
alcohols. Ester gum has drying properties and is used in paints, varnishes,
and lacquers. Rosin has been used to depackage integrated circuits from their
epoxy coatings.
Synonyms[1R-(1a,4ab,4ba,10a(a)]-1,2,3,4,4a,4
b,5,6,10,10a-Decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic
acid
13-Isoporpylpodocarpa-7,13-dien-15-oic acid
Abietic acid
Sylvic
acid
13-Isopropylpodocarpa-7,13-dien-15-oic acid
7,13-Abietadien-18-oic
acid
AI3-17273
Abietate
CCRIS 3183
EINECS 208-178-3
Kyselina
abietova
NSC 25149
UsesAdhesive tape
Brown soaps
Chewing gums
Cleansing agents
Deodorizing agent in cooling fluids
Cosmetics
Cutting fluids
Dental impression materials
Deodorizing agent
Glue
Inks
Insulating tapes
Ostomy appliances
Papers
Polishes
Sealants
Soldering fluxes
Ulcer bandages
Varnishes
Violinists' rosin
Cross-ReactionsColophony
Dihydroabietyl alcohol
Unusual ReactionsContact urticaria
Back to list of contact allergens
Referenties
1. |
Wahlberg JE. Abietic acid and colophony. Contact
Dermatitis 1978;4(1):55. |
2. |
Karlberg AT, Boman A, Wahlberg JE. Allergenic
potential of abietic acid, colophony and pine resin-HA. Clinical and
experimental studies. Contact Dermatitis 1980;6(7):481-487. |
3. |
Karlberg AT, et al. Is abietic acid the allergenic
component of colophony? Contact Dermatitis 1985;13(4):209-215. |
4. |
Karlberg AT. Pure abietic acid is not allergenic
[letter; comment]. Contact Dermatitis 1989;21(4):282-285. |
5. |
Hausen BM et al. Contact allergy due to colophony
(III). Sensitizing potency of resin acids and some related products
[see comments]. Contact Dermatitis 1989;20(1):41-50. |
6. |
Hausen BM, Krohn K, Budianto E. Contact allergy
due to colophony (VII). Sensitizing studies with oxidation products
of abietic and related acids. Contact Dermatitis 1990;23(5):352-358. |
7. |
Shao LP et al. The allergenicity of glycerol
esters and other esters of rosin (colophony). Contact Dermatitis 1993;28(4):229-234. |
8. |
Gafvert E et al. Allergenicity of rosin (colophony)
esters (II). Glyceryl monoabietate identified as contact allergen. Contact
Dermatitis 1994;31(1):11-17. |
9. |
Gafvert E. Allergenic components in modified
and unmodified rosin. Chemical characterization and studies of allergenic
activity. Acta Dermato-Venereologica. Supplementum 1994;184:1-36. |
10. |
Fisher AA. Allergic contact dermatitis in a violinist.
The role of abietic acid - a sensitizer in rosin (colophony) - as the
causative agent. Cutis 1981;27(5):466, 468, 473. |
11. |
El Sayed F, Manzur F, Bayle P, Marguery MS, Bazex
J. Contact urticaria from abietic acid. Contact dermatitis 1995;32(6):361-362. |
Auteur(s):dr. Jan R. Mekkes. Dermatoloog, Amsterdam
UMC.