|
Formula |
CAS |
|
C14H10O4 |
94-36-0 |
CAS: Chemical Abstract Service Registry Number
Background
Benzoyl peroxide is an antimicrobial and keratolytic agent used in the treatment of acne. It is also present in foods. It is a catalyst for cross-linking in
the production of plastics and is occasionally used in acrylic resin systems (eg. composite dental fillings, dental prothesis: it is formed during the cross-linking process and will therefore not be mentioned as a component of the resin system).
It is used in stretching tapes used in the treatment of leg ulcers.
Benzoyl peroxide is metabolized in the skin to benzoic acid. Positive patch tests to benzoyl peroxide may be explained by a contact allergy to benzoic acid.
Synonyms
Acetoxyl
Acnegel
Benzac
Benzaknen
Debroxide
Desanden
Benzagel 10
Benoxyl
Benzoyl peroxide
Benzoyl superoxide
Dibenzoyl peroxide
Lucidol
Nericur
Oxy-5, Oxy 10
PanOxyl
Peroxydex
Persadox
Persa-gel
sanoxit
Theraderm
Xerac BP 5
Xerac BP 10
Uses
Acne medications
Bone cement and dental acrylates
Dental prosthesis
Flour
Initiator in polymerization
Keratolytic
Oils
Plastic catalyst
Stretching tapes for leg ulcers
Cross-Reactions
Unusual Reactions
Airborne
Discoloration of hair
Postinflammatory hyper- and hypopigmentation
References
|
1. |
Caro, I., Connubial contact dermatitis to benzoyl peroxide. Contact Dermatitis, 1976. 2(6): p. 362. |
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2. |
Leyden, J.J. and A.M. Kligman, Contact sensitization to benzoyl peroxide. Contact Dermatitis, 1977. 3(5): p. 273-5. |
|
3. |
Kaaber, S., H. Thulin, and E. Nielsen, Skin sensitivity to denture base materials in the burning mouth syndrome. Contact Dermatitis, 1979. 5(2): p. 90-6. |
|
4. |
Jensen, O., S.H. Petersen, and L. Vesterager, Contact sensitization to benzoyl peroxide following topical treatment of chronic leg ulcers. Contact Dermatitis, 1980. 6(3): p. 179-82. |
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5. |
Vena, G.A., G. Angelini, and C.L. Meneghini, Contact dermatitis to benzoyl peroxide. Contact Dermatitis, 1982. 8(5): p. 338. |
|
6. |
Lindemayr, H. and M. Drobil, Contact sensitization to benzoyl peroxide. Contact Dermatitis, 1981. 7(3): p. 137-40. |
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7. |
Agathos, M. and H.J. Bandmann, Benzoyl peroxide contact allergy in leg ulcer patients. Contact Dermatitis, 1984. 11(5): p. 316-7. |
|
8. |
Balato, N., et al., Benzoyl peroxide reactions in acne patients. Contact Dermatitis, 1984. 10(4): p. 255. |
|
9. |
Angelini, G., G.A. Vena, and C.L. Meneghini, Allergic contact dermatitis to some medicaments. Contact Dermatitis, 1985. 12(5): p. 263-9. |
|
10. |
Haustein, U.F., L. Tegetmeyer, and V. Ziegler, Allergic and irritant potential of benzoyl peroxide. Contact Dermatitis, 1985. 13(4): p. 252-7. |
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11. |
Mora Morillas, I., et al., Is benzoyl peroxide an irritant or sensitizer?. Contact Dermatitis, 1987. 16(4): p. 232-3. |
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12. |
Morelli, R., et al., Contact dermatitis due to benzoyl peroxide. Contact Dermatitis, 1989. 20(3): p. 238-9. |
|
13. |
van Joost, T., et al., Purpuric contact dermatitis to benzoyl peroxide. Journal of the American Academy of Dermatology, 1990. 22(2 Pt 2): p. 359-61. |
|
14. |
Vincenzi, C., et al., Allergic contact dermatitis due to benzoyl peroxide in an arm prosthesis. Contact Dermatitis, 1991. 24(1): p. 66-7. |
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15. |
Bonnekoh, B. and H.F. Merk, Airborne allergic contact dermatitis from benzoyl peroxide as a bleaching agent of candle wax. Contact Dermatitis, 1991. 24(5): p. 367-8. |
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16. |
Dutree-Meulenberg, R.O., M.M. Kozel, and T. van Joost, Burning mouth syndrome: a possible etiologic role for local contact hypersensitivity. Journal of the American Academy of Dermatology, 1992. 26(6): p. 935-40. |
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17. |
Quirce, S., et al., Occupational airborne contact dermatitis due to benzoyl peroxide. Contact Dermatitis, 1993. 29(3): p. 165-6. |
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18. |
Sevila, A., et al., Contact dermatitis in children. Contact Dermatitis, 1994. 30(5): p. 292-4. |
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19. |
Eaglstein, W.H., Allergic contact dermatitis to benzoyl peroxide. Report of cases. Archives of Dermatology, 1968. 97(5): p. 527. |
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20. |
Fisher, A.A., Consort contact dermatitis. Cutis, 1979. 24(6): p. 595-6, 668. |
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21. |
Cotterill, J.A., Benzoyl peroxide. Acta Dermato-Venereologica. Supplementum, 1980. Suppl(89): p. 57-63. |
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22. |
Mann, R.J. and R.D. Peachey, Allergen transfer between individuals as a cause of contact dermatitis. Contact Dermatitis, 1981. 7(3): p. 164-5. |
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23. |
Tkach, J.R., Allergic contact urticaria to benzoyl peroxide. Cutis, 1982. 29(2): p. 187-8. |
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24. |
Greiner D, Weber J, Kaufmann R, Boehncke W-H. Benzoyl peroxide as a contact allergen in adhesive tape. Contact Dermatitis 1999;41:233 |
13-06-2011
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