Budesonide

codes geen / geen

 

 

Formula

CAS

C25H34O6

51333-22-3

 
CAS: Chemical Abstract Service Registry Number
 

Background

Budesonide is a nonhalogenated corticosteroid for use in topical preparations and for the treatment of rhinitis and asthma.

 

Synonyms

Budesonide
16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione
(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde
S-1320
Budeson
Preferid
Pulmicort
Rhinocort
Spirocort

 

Uses

Anti-inflammatory agent
Nasal spray

 

Cross-Reactions

It belongs to the group B (triamcinolone acetonide) grouping of corticosteroids (Coopman et al). According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.

 

Unusual Reactions

 

 

References

1.

van Hecke, E. and L. Temmerman, Contact allergy to the corticosteroid budesonide. Contact Dermatitis, 1980. 6(7): p. 509.

2.

Meding, B. and E. Dahlberg, Contact allergy to budesonide in a nasal spray. Contact Dermatitis, 1986. 14(4): p. 253-4.

3.

Coopman, S., H. Degreef, and A. Dooms-Goossens, Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. British Journal of Dermatology, 1989. 121(1): p. 27-34.

4.

Jerez, J., et al., Allergic contact dermatitis from budesonide. Contact Dermatitis, 1990. 22(4): p. 231-2.

5.

Gamboa, P.M., I. Jauregui, and I. Antepara, Contact dermatitis from budesonide in a nasal spray without cross-reactivity to amcinonide. Contact Dermatitis, 1991. 24(3): p. 227-8.

6.

Hayakawa, R., et al., Allergic contact dermatitis due to budesonide. Contact Dermatitis, 1991. 24(2): p. 136-7.

7.

Noda, H., et al., Contact dermatitis due to budesonide [published erratum appears in Contact Dermatitis 1992 Jan;26(1):71]. Contact Dermatitis, 1991. 25(1): p. 72-3.

8.

Peris-Tortajada, A., et al., Contact allergy to topical budesonide. Journal of Allergy & Clinical Immunology, 1991. 87(2): p. 597-8.

9.

Piraccini, B.M., et al., Contact dermatitis due to budesonide. Contact Dermatitis, 1991. 24(1): p. 54-5.

10.

Burden, A.D. and M.H. Beck, Contact hypersensitivity to topical corticosteroids. British Journal of Dermatology, 1992. 127(5): p. 497-500.

11.

Dooms-Goossens, A. and M. Morren, Results of routine patch testing with corticosteroid series in 2073 patients. Contact Dermatitis, 1992. 26(3): p. 182-91.

12.

Faria, A., J. Marote, and C. de Freitas, Contact allergy to budesonide in a nasal spray. Contact Dermatitis, 1992. 27(1): p. 57.

13.

Hayakawa, R., et al., A case of budesonide contact allergy. Contact Dermatitis, 1992. 26(2): p. 128-9.

14.

Wilkinson, S.M., A.G. Smith, and J.S. English, Erythroderma following the intradermal injection of the corticosteroid budesonide. Contact Dermatitis, 1992. 27(2): p. 121-2.

15.

Noda, H., et al., Contact sensitivity and cross-reactivity of budesonide. Contact Dermatitis, 1993. 28(4): p. 212-5.

16.

Veraldi, S., D. Fallahdar, and A. Riboldi, Allergic contact dermatitis from budesonide. Contact Dermatitis, 1993. 28(2): p. 116.

17.

Corazza, M., et al., Compound allergy to topical budesonide. Contact Dermatitis, 1994. 30(4): p. 246-7.

18.

Iglesias-Cadarso, A., et al., Allergic contact dermatomucositis to budesonide. Journal of Allergy & Clinical Immunology, 1994. 94(3 Pt 1): p. 559-60.

19.

Jorro, G., et al., Contact allergy to topical budesonide in nasal spray. Contact Dermatitis, 1993. 28(4): p. 254.

20.

Okano, M., Contact dermatitis due to budesonide: report of five cases and review of the Japanese literature. International Journal of Dermatology, 1994. 33(10): p. 709-15.

21.

Lepoittevin, J.P., J. Drieghe, and A. Dooms-Goossens, Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids [see comments]. Archives of Dermatology, 1995. 131(1): p. 31-7.

 

 

 

 

 

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