Colophony (colofonium)

codes geen / geen

 

 

 

Formula

CAS

 

1065-31-2

 
CAS: Chemical Abstract Service Registry Number
 

Background

Colophony is derived mainly from Pinus palustris and Pinus caribaea and is a sticky amber material in its crude form. It consists of 90% resin acids and 10% neutral matter. It contains several allergens including oxidation products of abietic acid and dehydroabietic acid. 

 

Synonyms

Abietic acid
Abietic alcohol
Abietyl alcohol
Abitol
Colophony
Dercolyte ZS
Dertomal 18
Dertophene 18
Foral 105
Granolite SG
Gum rosin
Hercolyn D
Methyl abietate alcohol
Resina terebinthinae
Rosin
Rosin gum
Staybelite 10
Tall oil
W-W wood rosin

 

Uses

Adhesives
Athletic grip aid
Brown soaps
Chewing gum
Cleansing agents
Cosmetics mascara, rouge, eye shadow soaps
Cutting fluids
Dental cements and impression pastes
Glue tackifiers
Insulating tapes
Ostomy appliances
Paper
Pine oil cleaners
Pine tree sawdust
Periodontal packings
Polishes and waxes
Printing inks
Soldering fluxes
Surface coatings
Topical medicaments
Ulcer bandages
Varnishes
Violin bow rosin

 

Cross-Reactions

Balsam Peru
Dihydroabietyl alcohol
Oil of turpentine
Pine resin
Spruce resin
Wood tars

 

Unusual Reactions

 

 

References

1.

Burry, J.N., Contact dermatitis from radiata pine. Contact Dermatitis, 1976. 2(5): p. 262-3.

2.

Dooms-Goossens, A., et al., Turpentine-induced hypersensitivity to peppermint oil. Contact Dermatitis, 1977. 3(6): p. 304-8.

3.

Husain, S.L., Contact dermatitis in the West of Scotland. Contact Dermatitis, 1977. 3(6): p. 327-32.

4.

Ducombs, G., Allergy to colophony. Contact Dermatitis, 1978. 4(2): p. 118-9.

5.

Wahlberg, J.E., Abietic acid and colophony. Contact Dermatitis, 1978. 4(1): p. 55.

6.

Camarasa, J.M., First epidemiological study of contact dermatitis in Spain - 1977. Spanish Contact Dermatitis Research Group. Acta Dermato-Venereologica. Supplementum, 1979. 59(85): p. 33-7.

7.

Dooms-Goossens, A., H. Degreef, and E. Luytens, Dihydroabietyl alcohol (Abitol): a sensitizer in mascara. Contact Dermatitis, 1979. 5(6): p. 350-3.

8.

Fregert, S., Colophony in cutting oil and in soap water used as cutting fluid. Contact Dermatitis, 1979. 5(1): p. 52.

9.

Raith, L. and E. Rosenstock, [Contact dermatitis to colophony in cellophane rings of Gothatest (author's transl)]. Dermatologische Monatsschrift, 1979. 165(2): p. 133-4.

10.

Wilkinson, D.S. and J.D. Wilkinson, Comparison of patch test results in two adjacent areas of England-I. (Industrial allergens). Acta Dermato-Venereologica. Supplementum, 1979. 59(85): p. 189-92.

11.

Karlberg, A.T., A. Boman, and J.E. Wahlberg, Allergenic potential of abietic acid, colophony and pine resin-HA. Clinical and experimental studies. Contact Dermatitis, 1980. 6(7): p. 481-7.

12.

Barth, J.H., Colophony sensitivity--a regional variant. Contact Dermatitis, 1981. 7(3): p. 165-6.

13.

Dahlquist, I., Contact allergy to colophony and formaldehyde from sand cores. Contact Dermatitis, 1981. 7(3): p. 167-8.

14.

Fisher, A.A., Allergic contact dermatitis in a violinist. The role of abietic acid--a sensitizer in rosin (colophony)--as the causative agent. Cutis, 1981. 27(5): p. 466, 468, 473.

15.

Hausen, B.M., A. Kuhlwein, and K.H. Schulz, [Colophony allergy. A contribution to the origin, chemistry, and uses of colophony and modified colophony products, 1.]. Dermatosen in Beruf und Umwelt. Occupational & Environmental Dermatoses, 1982. 30(4): p. 107-15.

16.

Widstrom, L., Contact allergy to colophony in soldering flux. Contact Dermatitis, 1983. 9(3): p. 205-7.

17.

Dooms-Goossens, A., et al., Colophony-induced sensitivity to Juniperus chinensis L. "Hetzii"?. Contact Dermatitis, 1984. 10(3): p. 185-7.

18.

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19.

James, W.D., Allergic contact dermatitis to a colophony derivative. Contact Dermatitis, 1984. 10(1): p. 6-10.

20.

Mathias, C.G. and R.M. Adams, Allergic contact dermatitis from rosin used as soldering flux. Journal of the American Academy of Dermatology, 1984. 10(3): p. 454-6.

21.

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22.

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23.

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24.

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25.

Bruze, M., Simultaneous reactions to phenol-formaldehyde resins colophony/hydroabietyl alcohol and balsam of Peru/perfume mixture. Contact Dermatitis, 1986. 14(2): p. 119-20.

26.

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27.

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28.

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29.

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30.

Aberer, W., Allergy to colophony acquired backstage. Contact Dermatitis, 1987. 16(1): p. 34-6.

31.

Goh, C.L. and S.K. Ng, Airborne contact dermatitis to colophony in soldering flux. Contact Dermatitis, 1987. 17(2): p. 89-91.

32.

Monk, B., Allergic contact dermatitis to colophony in a wart remover. Contact Dermatitis, 1987. 17(4): p. 242.

33.

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34.

Rivers, J.K. and R.J. Rycroft, Occupational allergic contact urticaria from colophony. Contact Dermatitis, 1987. 17(3): p. 181.

35.

de Groot, A.C., et al., The role of contact allergy in the spectrum of adverse effects caused by cosmetics and toiletries. Contact Dermatitis, 1988. 19(3): p. 195-201.

36.

Fisher, A.A., Allergic contact dermatitis due to rosin (colophony) in eyeshadow and mascara. Cutis, 1988. 42(6): p. 507-8.

37.

Goh, C.L., An epidemiological comparison between hand eczema and non-hand eczema. British Journal of Dermatology, 1988. 118(6): p. 797-801.

38.

Goncalo, S., F. Cabral, and M. Goncalo, Contact sensitivity to oak moss. Contact Dermatitis, 1988. 19(5): p. 355-7.

39.

Hogan, D.J., M. Hill, and P.R. Lane, Results of routine patch testing of 542 patients in Saskatoon, Canada. Contact Dermatitis, 1988. 19(2): p. 120-4.

40.

Karlberg, A.T., Colophony-free wart removers in Sweden [letter]. Contact Dermatitis, 1988. 18(4): p. 254.

41.

Karlberg, A.T., et al., Contact allergy to dehydroabietic acid derivatives isolated from Portuguese colophony. Contact Dermatitis, 1988. 19(3): p. 166-74.

42.

Karlberg, A.T., A. Boman, and J.L. Nilsson, Hydrogenation reduces the allergenicity of colophony (rosin). Contact Dermatitis, 1988. 19(1): p. 22-9.

43.

Karlberg, A.T. and C. Liden, Comparison of colophony patch test preparations. Contact Dermatitis, 1988. 18(3): p. 158-65.

44.

Matos, J., et al., Occupational dermatitis from colophony. Contact Dermatitis, 1988. 18(1): p. 53-4.

45.

Christophersen, J., et al., Clinical patch test data evaluated by multivariate analysis. Danish Contact Dermatitis Group. Contact Dermatitis, 1989. 21(5): p. 291-9.

46.

Hausen, B.M., et al., Contact allergy due to colophony (III). Sensitizing potency of resin acids and some related products [see comments]. Contact Dermatitis, 1989. 20(1): p. 41-50.

47.

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48.

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49.

Krutmann, J., et al., Airborne contact dermatitis from colophony: phototoxic reaction?. Contact Dermatitis, 1989. 21(4): p. 275-6.

50.

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51.

Lane, P.R., V.L. Harms, and D.J. Hogan, Patch testing in actinic prurigo. Contact Dermatitis, 1989. 21(4): p. 249-54.

52.

Olaguibel, J., et al., Passive transfer of contact sensitivity to colophony as a complication of an allogenic bone-marrow transplant. Contact Dermatitis, 1989. 20(3): p. 182-4.

53.

Ayala, F., et al., The use of laboratory methods in contact dermatitis induced by composite materials [published erratum appears in Contact Dermatitis 1990 Nov;23(5):384]. Contact Dermatitis, 1990. 22(5): p. 262-6.

54.

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55.

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56.

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57.

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58.

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59.

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60.

van den Akker, T.W., et al., Contact allergy to spices. Contact Dermatitis, 1990. 22(5): p. 267-72.

61.

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62.

Barbaud, A., et al., Contact allergy to colophony in Chinese Musk and Tiger-Bone Plaster. Contact Dermatitis, 1991. 25(5): p. 324-6.

63.

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64.

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65.

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66.

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67.

Castiglioni, G., A. Carosso, and F. Nebiolo, Contact dermatitis from colophony in a horticulturalist. Contact Dermatitis, 1992. 26(4): p. 271.

68.

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69.

Kanerva, L., et al., Contact dermatitis from telefax paper. Contact Dermatitis, 1992. 27(1): p. 12-5.

70.

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71.

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72.

Lim, J.T., et al., Changing trends in the epidemiology of contact dermatitis in Singapore. Contact Dermatitis, 1992. 26(5): p. 321-6.

73.

Lodi, A., et al., Allergy to castor oil and colophony in a wart remover. Contact Dermatitis, 1992. 26(4): p. 266-7.

74.

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75.

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76.

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77.

Hausen, B.M., et al., Contact allergy due to colophony. (IX). Sensitization studies with further products isolated after oxidative degradation of resin acids and colophony. Contact Dermatitis, 1993. 29(5): p. 234-40.

78.

Saha, M., et al., Footwear dermatitis. Contact Dermatitis, 1993. 28(5): p. 260-4.

79.

Shao, L.P., et al., The allergenicity of glycerol esters and other esters of rosin (colophony). Contact Dermatitis, 1993. 28(4): p. 229-34.

80.

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81.

Gafvert, E., Allergenic components in modified and unmodified rosin. Chemical characterization and studies of allergenic activity. Acta Dermato-Venereologica. Supplementum, 1994. 184: p. 1-36.

82.

Gafvert, E., et al., Allergenicity of rosin (colophony) esters (II). Glyceryl monoabietate identified as contact allergen. Contact Dermatitis, 1994. 31(1): p. 11-7.

83.

Karlberg, A.T., Identification and sensitization studies of colophony components [letter]. Contact Dermatitis, 1994. 31(4): p. 279-80.

84.

Lewis, F.M., D.J. Gawkrodger, and C.I. Harrington, Colophony: an unusual factor in pruritus vulvae. Contact Dermatitis, 1994. 31(2): p. 119.

85.

Meding, B., L. Barregard, and K. Marcus, Hand eczema in car mechanics. Contact Dermatitis, 1994. 30(3): p. 129-34.

86.

Selvaag, E., B. Eriksen, and P. Thune, Contact allergy due to tea tree oil and cross-sensitization to colophony. Contact Dermatitis, 1994. 31(2): p. 124-5.

87.

Thorneby-Andersson, K. and C. Hansson, Allergic contact dermatitis from colophony in waxes for polishing spectacle frames. Contact Dermatitis, 1994. 31(2): p. 126-7.

88.

Fischer, T., et al., Skin disease and contact sensitivity in house painters using water-based paints, glues and putties. Contact Dermatitis, 1995. 32(1): p. 39-45.

89.

89. Koh, D., et al., Colophony in bindi adhesive. Contact Dermatitis, 1995. 32(3): p. 186.

90.

Menage, H., et al., Contact and photocontact sensitization in chronic actinic dermatitis: sesquiterpene lactone mix is an important allergen. British Journal of Dermatology, 1995. 132(4): p. 543-7.

91.

Danielsen H. Airborne allergic contact dermatitis from colophony in a car. Contact Dermatitis 1999;41:51

 

 

 

 

 

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