CAS: Chemical Abstract Service Registry Number
Dichlorophene is a fungicide and bactericide used in dentifrices, shampoos,
antiperspirant and deodorant creams, powder, toilet waters, and preparations
for dermatophytosis of the foot. It is also used extensively as a mildewcide
to treat and preserve cotton fibers, various fabrics, paper, synthetic
leather lattices, and some adhesive tape backings.
Dichlorophene is a more potent sensitizer than hexachlorophene. Although
closely related chemically, they rarely cross-react. The U.S. Food and
Drug Administration has restricted greatly the use of hexachlorophene for
its possible toxic, but not allergic, effect.
G-4 (Compound G4)
Bandages (soft casts)
Dentifrices, toothpaste, and mouthwashes
Soaps and cleansers
Treated fabrics, papers, adhesives, and bandages.
A.A. and I. Tobin, Sensitivity to compound G-4 ('Dichlorophene')
in dentrifices. Journal of The American Medical Association, 1953. 151: p. 988.
Dichlorophene allergy. Annals of Allergy, 1966. 24: p. 437.
Dichlorphene (G-4) allergy. Archives of Dermatology,
1970. 102: p. 515.
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