|
Formula |
CAS |
|
C13H6Cl6O2 |
70-30-4 |
CAS: Chemical Abstract Service Registry Number
Background
Hexachlorophene is used as a topical antiseptic. Because of potential neurotoxicity in humans, the FDA has regulated its use.
Synonyms
2,2´-Methylenebis[3,4,6-trichlorophenol]
2,2´-Dihydroxy-3,3´,5,5´,6,6´-hexachlorodiphenylmethane
bis(3,5,6-trichloro-2-hydroxyphenyl)methane
AT-7
Bilevon
Dermadex
Exofene
G-11
Gamophen
Hexachlorophene
Hexosan
pHisohex
Surgi-Cen
Surofene
Uses
pHisoHex
Soaps, cleansers, shampoos, and shaving cream.
Cross-Reactions
Bithionol
Halogenated salicylanilides
Unusual Reactions
Photoallergy
References
|
1. |
Fisher, A.A., F. Pascher, and N.B. Kanof, Allergic contact dermatitis due to ingredients of vehicles. A "vehicle tray" for patch testing. Archives of Dermatology, 1971. 104(3): p. 286-90. |
|
2. |
Wilkinson, D.S. and E. Cronin, Contact dermatitis XIX. British Journal of Dermatology, 1972. 87(4): p. 400-2. |
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3. |
Iden, D.L. and A.L. Schroeter, The vehicle tray revisited: the use of the vehicle tray in assessing allergic contact dermatitis by a 24-hour application method. Contact Dermatitis, 1977. 3(3): p. 122-6. |
|
4. |
Wilkinson, D.S., Hexachlorophene bath hazard [letter]. Contact Dermatitis, 1978. 4(3): p. 172. |
|
5. |
Kaidbey, K.H. and A.M. Kligman, Photomaximization test for identifying photoallergic contact sensitizers. Contact Dermatitis, 1980. 6(3): p. 161-9. |
12-11-2011
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