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Formula |
CAS |
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C25H36O6 |
13609-67-1 |
CAS: Chemical Abstract Service Registry Number
Background
Hydrocortisone-17-butyrate is a mild potency topical non-fluorinated corticosteroid with low systemic effects. It is used for the treatment of corticosteroid responsive dermatoses. It is classified as group D by Coopman et al. According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.
Synonyms
Hydrocortisone-17-butyrate
Alfason
Locoid
Plancol
Uses
Anti-inflammatory
Topical medications
Cross-Reactions
Unusual Reactions
References
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1. |
Brandao, F.M. and F.M. Camarasa, Contact allergy to hydrocortisone 17-butyrate. Contact Dermatitis, 1979. 5(6): p. 354-6. |
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2. |
van Waadenoijen Kernekamp, A.S. and W.G. van Ketel, Contact allergy to hydrocortisone-17-butyrate. Contact Dermatitis, 1979. 5(4): p. 268-9. |
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3. |
Brown, R., Allergy to hydrocortisone-17-butyrate. Contact Dermatitis, 1980. 6(7): p. 504-5. |
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4. |
Yoshikawa, K., K. Watanabe, and N. Mizuno, Contact allergy to hydrocortisone 17-butyrate and pyridoxine hydrochloride. Contact Dermatitis, 1985. 12(1): p. 55-6. |
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5. |
Coopman, S., H. Degreef, and A. Dooms-Goossens, Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. British Journal of Dermatology, 1989. 121(1): p. 27-34. |
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6. |
Dooms-Goossens, A.E., et al., Contact allergy to corticosteroids: a frequently missed diagnosis?. Journal of the American Academy of Dermatology, 1989. 21(3 Pt 1): p. 538-43. |
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7. |
Reitamo, S., A.I. Lauerma, and L. Forstrom, Detection of contact hypersensitivity to topical corticosteroids with hydrocortisone-17-butyrate. Contact Dermatitis, 1989. 21(3): p. 159-65. |
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8. |
Dunkel, F.G., P. Elsner, and G. Burg, Contact allergies to topical corticosteroids: 10 cases of contact dermatitis. [Review]. Contact Dermatitis, 1991. 25(2): p. 97-103. |
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9. |
Lauerma, A.I., Screening for corticosteroid contact sensitivity. Comparison of tixocortol pivalate, hydrocortisone-17-butyrate and hydrocortisone. Contact Dermatitis, 1991. 24(2): p. 123-30. |
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10. |
Lauerma, A.I., S. Reitamo, and H.I. Maibach, Systemic hydrocortisone/cortisol induces allergic skin reactions in presensitized subjects. Journal of the American Academy of Dermatology, 1991. 24(2 Pt 1): p. 182-5. |
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11. |
Marston, S., Contact dermatitis from cetostearyl alcohol in hydrocortisone butyrate lipocream, and from lanolin. Contact Dermatitis, 1991. 24(5): p. 372. |
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12. |
Burden, A.D. and M.H. Beck, Contact hypersensitivity to topical corticosteroids. British Journal of Dermatology, 1992. 127(5): p. 497-500. |
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13. |
Hisa, T., et al., Contact allergies to topical corticosteroids. Contact Dermatitis, 1993. 28(3): p. 174-9. |
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14. |
Lepoittevin, J.P., J. Drieghe, and A. Dooms-Goossens, Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids [see comments]. Archives of Dermatology, 1995. 131(1): p. 31-7. |
10-12-2011
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