|
Formula |
CAS |
|
C5H8O2 |
80-62-6 |
CAS: Chemical Abstract Service Registry Number
Background
Methyl ester of methacrylic acid which polymerizes forming a clear plastic
known as Lucite, Plexiglas, Perspex.
Kopula et al. found positive reactions to methyl methacrylate in 32%
of all acrylate-allergic patients and 10% of nail-allergic patients. They
suggested that it may not be a good screening allergen for individuals
allergic to nail acrylates.
Fisher showed that the usual sensitizing agent of acrylic prostheses
was methyl methacrylate monomer. Kanerva et al successfully coated an allergenic
methacrylate prosthesis with a UV light-cured coating.
Synonyms
Acrylate monomer
Acrylate plastic
Acrylate resin
Methyl methacrylate
MMA
Uses
Methacrylic monomer used in
Cosmetics (artificial sculptured nails, nail extenders)
Dental (dentures, fillings, coatings)
Medical (adhesive tape, contact lenses, hearing aids, surgical prostheses
bone cement)
Industrial (sealants, printing plates, inks, and coatings of glass,
rubber, and textiles)
Cross-Reactions
Unusual Reactions
References
|
1. |
Marshall, M., A. Guill, and R.B. Odom, Hearing aid dermatitis. Archives of Dermatology, 1978. 114(7): p. 1050-1. |
|
2. |
Nethercott, J.R., Skin problems associated with multifunctional acrylic monomers in ultraviolet curing inks. British Journal of Dermatology, 1978. 98(5): p. 541-52. |
|
3. |
Fisher, A.A., Cross reactions between methyl methacrylate monomer and acrylic monomers presently used in acrylic nail preparations. Contact Dermatitis, 1980. 6(5): p. 345-7. |
|
4. |
van der Walle, H.B., et al., Sensitizing potential of 14 mono (meth) acrylates in the guinea pig. Contact Dermatitis, 1982. 8(4): p. 223-35. |
|
5. |
Estlander, T., R. Rajaniemi, and R. Jolanki, Hand dermatitis in dental technicians. Contact Dermatitis, 1984. 10(4): p. 201-5. |
|
6. |
Kassis, V., P. Vedel, and E. Darre, Contact dermatitis to methyl methacrylate. Contact Dermatitis, 1984. 11(1): p. 26-8. |
|
7. |
Mathias, C.G. and H.I. Maibach, Allergic contact dermatitis from anaerobic acrylic sealants. Archives of Dermatology, 1984. 120(9): p. 1202-5. |
|
8. |
Romaguera, C., F. Grimalt, and J. Vilaplana, Methyl methacrylate prosthesis dermatitis. Contact Dermatitis, 1985. 12(3): p. 172. |
|
9. |
van Joost, T., J. van Ulsen, and L.A. van Loon, Contact allergy to denture materials in the burning mouth syndrome. Contact Dermatitis, 1988. 18(2): p. 97-9. |
|
10. |
Fousssereau, J., et al., Contact dermatitis from methyl methacrylate in an above-knee prosthesis. Contact Dermatitis, 1989. 20(1): p. 69-70. |
|
11. |
Kanerva, L., T. Estlander, and R. Jolanki, Allergic contact dermatitis from dental composite resins due to aromatic epoxy acrylates and aliphatic acrylates. Contact Dermatitis, 1989. 20(3): p. 201-11. |
|
12. |
Kanzaki, T., et al., Contact stomatitis due to methyl methacrylate monomer. Contact Dermatitis, 1989. 20(2): p. 146-8. |
|
13. |
Farli, M., et al., Occupational contact dermatitis in 2 dental technicians. Contact Dermatitis, 1990. 22(5): p. 282-7. |
|
14. |
Corazza, M., A. Virgili, and S. Martina, Allergic contact stomatitis from methyl methacrylate in a dental prosthesis, with a persistent patch test reaction. Contact Dermatitis, 1992. 26(3): p. 210-1. |
|
15. |
Kanerva, L., et al., Occupational allergic contact dermatitis caused by exposure to acrylates during work with dental prostheses. Contact Dermatitis, 1993. 28(5): p. 268-75. |
|
16. |
Vilaplana, J., C. Romaguera, and F. Cornellana, Contact dermatitis and adverse oral mucous membrane reactions related to the use of dental prostheses. Contact Dermatitis, 1994. 30(2): p. 80-4. |
|
17. |
Kanerva, L., et al., Successful coating of an allergenic acrylate-based dental prosthesis. American Journal of Contact Dermatitis, 1995. 6(1): p. 24-27. |
|
18. |
Koppula, S., J. Fellman, and F. Storrs, Screening allergens for acrylate dermatitis associated with artificial nails. American Journal of Contact Dermatitis, 1995. 6(2): p. 78-85. |
13-08-2011
(JRM) - www.huidziekten.nl