Quaternium 15 (Dowicil 200)

codes geen / geen

 

 

Formula

CAS

 

51229-78-8

 
CAS: Chemical Abstract Service Registry Number
 

Background

Quaternium-15 is a broad-spectrum preservative found in many cosmetics and personal care products. Quaternium-15 is one of the formaldehyde-releasing preservatives that include imidazolidinyl urea, diazolidinyl urea, 2-bromo-2-nitropropane-l,3-diol, DMDM (dimethylolmethyl)hydantoin, and tris (hydroxymethyl) nitromethane. Although quaternium-l 5 does release small amounts of formaldehyde, not all patients who are allergic to quaternium-15 are allergic to formaldehyde and vice versa.

 

Synonyms

Azoniaadamantane chloride
Chloroallyl methanamine chloride
Cis-l-(3-chloroallyl)3,5,7-triaza-l-azoniaadamantane chloride
Dowicil 75, 100, 200 (chemically similar)
Dowicil 200
1-(3-Choroallyl)-3,5,7-triaza-1-azoniaadamantane chloride
Methanamine-3-chloroallylochloride
N-(3-chloroallyl) hexaminium chloride
Preventol D1
Quaternium 15

 

Uses

Adhesives
Construction materials
Cosmetics (creams, lotions, shampoos, soaps, etc.)
Inks
Jointing cements
Latex paints
Metal working fluids
Over-the-counter topical medicaments
Paper or paperboard
Polishes

 

Cross-Reactions

Formaldehyde

 

Unusual Reactions

 

 

References

 1.

Ford, G.P. and M.H. Beck, Reactions to Quaternium 15, Bronopol and Germall 115 in a standard series. Contact Dermatitis, 1986. 14(5): p. 271-4.

 2.

Tosti, A., B.M. Piraccini, and F. Bardazzi, Occupational contact dermatitis due to quaternium 15. Contact Dermatitis, 1990. 23(1): p. 41-2.

 3.

Marren, P., et al., Occupational contact dermatitis due to quaternium 15 presenting as nail dystrophy. Contact Dermatitis, 1991. 25(4): p. 253-5.

 4.

Perrenoud, D., et al., Frequency of sensitization to 13 common preservatives in Switzerland. Swiss Contact Dermatitis Research Group. Contact Dermatitis, 1994. 30(5): p. 276-9.

 

 

 

 

 

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