Thiomersal (Thimerosal, Merthiolate)

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Formula

CAS

C9H9HgNaO2S

54-64-8

 
CAS: Chemical Abstract Service Registry Number
 

Background

Thiomersal is used as an antiseptic and a preservative in topical medicaments, cosmetics, and vaccines.
It should be noted that thiomersal contains two distinct radicals, an organic mercury compound and a thiosalicylate. The allergic reactions may be from either compound.
Patients sensitive to thiomersal (Merthiolate) can be divided into three groups: 1) positive to thiomersal but negative to other mercurials and to thiosalicylic acid; 2) positive to thiomersal and to some other mercurials but negative to thiosalicylic acid; and 3) positive to thiomersal and to thiosalicylic acid, but negative to other mercurial 

 

Synonyms

Ethyl [2-mercaptobenzoato(2 )-O,S]-mercurate(1) sodium
Ethyl (2-mercaptobenzoato-S) mercury, sodium salt
Mercurothiolate
Merfamin
Merthiolate
Mertorgan
Merzonin
[(o-carboxyphenyl)thio]ethylmercury sodium salt
Sodium ethyl mercurithiosalicylate
Thiomersalate
Thimerosal

Thiomersal

  

Uses

Antiseptics
Antitoxins
Cosmetics
Eye preparations (contact lens solutions, eyedrops)
Skin testing antigens
Topical and systemic medicines (ear and nose drops, Tincture of Merthiolate)
Vaccines

 

Cross-Reactions

 

 

Unusual Reactions

 

 

References

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 2.

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51.

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